MLO Lab

Machine Learning in Oncology

Who we are

Our mission is the application and collaboration driven development of interpretable and statistically sound machine learning methods for understanding disease heterogeneity. As part of the DKTK/DKFZ and hosted by Frankfurt University we thrive to use machine learning for accelerating progress in personalised oncology.

We build on probabilistic machine learning to address computational challenges in three areas: translational single-cell genomics, computational proteomics and the integration of multi-omics data.

MLO Group Photo

Team

Principal Investigators

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Florian Buettner

Professor for Bioinformatics in Oncology

Machine Learning (ML), Precision Oncology, Multi-omics data integration

Postdoctoral Researchers

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Zahra Moslehi

Postdoctoral Researcher

Machine learning, Bioinformatics, Probabilistic modeling, Metric learning, Omics data analysis

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Adrien Jolly

Postdoctoral Researcher

Blood cell development, Modeling of cell population dynamics in vivo, Omics data analysis, Immune cell repertoire analysis

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Giuseppe Serra

Postdoctoral Researcher

Machine Learning, Federated Continual Learning, Trustworthy and Explainable AI

Doctoral Researchers

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Sebastian Gruber

Ph.D. Candidate

Calibration, Loss functions, Uncertainty Quantification

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Arber Qoku

Ph.D. Candidate

Probabilistic Machine Learning, Multi-omics Data Integration, Survival Analysis

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Sarmad Ahmad Khan

Ph.D. Candidate

Bioinformatics, Multi-omics Data Integration, Machine Learning, Oncological Studies, Calibration

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Kevin De Azevedo

Ph.D. Candidate

Bioinformatics, Omics Data Analysis, Machine Learning, Multi-omics Data Integration

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Sareh Ameri Far

Ph.D. Candidate

Multi-omics Data Analysis, Machine Learning, Oncology

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Yihao Liu

Ph.D. Candidate

Spatial Transcriptomics, Bone Marrow Microenvironment, Probabilistic Artificial intelligence, Graph Theory

Research Scientists

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Ali Yavuz Çakır

Research Scientist

Next Generation Sequencing Systems, Bioinformatics, Data Science, Human Genetics

Visiting Researchers

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Helong Gary Zhao

Visiting Scientist

Hematological malignancies, Clonal hematopoiesis, Precision Oncology, Cancer Prevention

Alumni

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Andreas Kopf

Guest Scientist

Machine Learning (ML), Deep Learning, Probabilistic Modeling

Teaching

In the summer term 2024 we offer Introduction to AI.

In the winter term 2024/2025 we offer a seminar on AI in Medicine.

Thesis Topics

We currently have no thesis topics to offer to BSc and MSc students.

Alumni

StudentTopicDegreeYear
Xiaoyan FengEncoding Pathway Gene Sets with Sparse Priors for Inferring Explainable Latent VariablesBachelor2021
Tim-Oliver EwaldSimulation and Evaluation of Distribution Shifts on Tumor ImagesBachelor2021
Tim DiedrichHidden Functional Activity in JOANABachelor2021
Lukas KuhnPost-hoc Uncertainty Calibration of Neural Networks via Kernel Density EstimationBachelor2022

Open Positions

We currently have no open positions.

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